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Ancient DNA from Guam and the peopling of the Pacific
Irina Pugach · Proceedings of the National Academy of Sciences
Ancient DNA from Guam and the peopling of the Pacific
Irina Pugach · Proceedings of the National Academy of Sciences
A genetic history of the pre-contact Caribbean
Daniel M. Fernandes · Nature
A genetic history of the pre-contact Caribbean
Daniel M. Fernandes · Nature
DOI: 10.1038/s41586-020-03053-2
A biomolecular anthropological investigation of William Adams, the first SAMURAI from England
Fuzuki Mizuno · Scientific Reports
A biomolecular anthropological investigation of William Adams, the first SAMURAI from England
Fuzuki Mizuno · Scientific Reports
DOI: 10.1038/s41598-020-78723-2
Tracing the Genetic Legacy of the Tibetan Empire in the Balti
Tracing the Genetic Legacy of the Tibetan Empire in the Balti
Kinship and social organization in Copper Age Europe. A cross-disciplinary analysis of archaeology, DNA, isotopes, and anthropology from two Bell Beaker cemeteries
Karl-Göran Sjögren · PLOS ONE
Kinship and social organization in Copper Age Europe. A cross-disciplinary analysis of archaeology, DNA, isotopes, and anthropology from two Bell Beaker cemeteries
Karl-Göran Sjögren · PLOS ONE
DOI: 10.1371/journal.pone.0241278
Blood group typing from whole-genome sequencing data
Blood group typing from whole-genome sequencing data
DOI: 10.1371/journal.pone.0242168
Ancient DNA reveals monozygotic newborn twins from the Upper Palaeolithic
Maria Teschler-Nicola · Communications Biology
Ancient DNA reveals monozygotic newborn twins from the Upper Palaeolithic
Maria Teschler-Nicola · Communications Biology
DOI: 10.1038/s42003-020-01372-8
Early medieval genetic data from Ural region evaluated in the light of archaeological evidence of ancient Hungarians
Veronika Csáky · Scientific Reports
Early medieval genetic data from Ural region evaluated in the light of archaeological evidence of ancient Hungarians
Veronika Csáky · Scientific Reports
DOI: 10.1038/s41598-020-75910-z
A dynamic 6000-year genetic history of Eurasia's Eastern Steppe
Choongwon Jeong · Cell
A dynamic 6000-year genetic history of Eurasia's Eastern Steppe
Choongwon Jeong · Cell
DOI: 10.1016/j.cell.2020.10.015
Comparison of Target Enrichment Strategies for Ancient Pathogen DNA
Anja Furtwängler · BioTechniques
Comparison of Target Enrichment Strategies for Ancient Pathogen DNA
Anja Furtwängler · BioTechniques
Denisovan ancestry and population history of early East Asians
Diyendo Massilani · Science
Denisovan ancestry and population history of early East Asians
Diyendo Massilani · Science
A systematic investigation of human DNA preservation in medieval skeletons
Cody Parker · Scientific Reports
A systematic investigation of human DNA preservation in medieval skeletons
Cody Parker · Scientific Reports
DOI: 10.1038/s41598-020-75163-w
Three Phases of Ancient Migration Shaped the Ancestry of Human Populations in Vanuatu
Mark Lipson · Current Biology
Three Phases of Ancient Migration Shaped the Ancestry of Human Populations in Vanuatu
Mark Lipson · Current Biology
DOI: 10.1016/j.cub.2020.09.035
The genomic formation of First American ancestors in East and Northeast Asia
The genomic formation of First American ancestors in East and Northeast Asia
DOI: 10.1101/2020.10.12.336628
Population genomics of the Viking world
Ashot Margaryan · Nature
Population genomics of the Viking world
Ashot Margaryan · Nature
DOI: 10.1038/s41586-020-2688-8
Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years
Joachim Burger · Current Biology
Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years
Joachim Burger · Current Biology
DOI: 10.1016/j.cub.2020.08.033
Yersinia pestis strains from Latvia show depletion of the pla virulence gene at the end of the second plague pandemic
古代基因组学研究已将鼠疫耶尔森氏菌（Y. pestis）鉴定为始于黑死病（1347-1353）的第二次鼠疫大流行（14-18世纪）的病原体。此次大流行中研究的鼠疫耶尔森氏菌菌株大多分离自西欧，人们对该细菌在东欧国家的多样性和微进化知之甚少。在本研究中，我们调查了从里加（拉脱维亚）两处墓地中发掘出的人类遗骸。历史证据表明，这些墓葬是17世纪鼠疫爆发的结果。我们从16具遗骸的牙齿中提取了DNA，并进行了散弹枪测序。宏基因组学数据分析显示，在四具遗骸中存在鼠疫耶尔森氏菌序列，证实这些被埋葬的个体是鼠疫的受害者。在两份样本中，鼠疫耶尔森氏菌DNA覆盖率足以进行基因组重建。随后的系统发育分析表明，里加菌株的多样性与已知的后黑死病基因组多样性相符。有趣的是，两株拉脱维亚分离株并未聚类在一起。此外，我们检测到含有pla基因的pPCP1质粒区域的覆盖度下降。进一步分析表明存在两个pPCP1质粒，一个含有pla基因区域，一个不含pla基因区域，并且只有一个细菌染色体，这表明同一种细菌携带两个不同的pPCP1质粒。此外，我们在大多数先前发表的后黑死病菌株中发现了相同的模式，但在黑死病菌株中没有发现。pla基因是人类感染和传播的重要毒力因子。因此，pla基因缺失的菌株的传播可能以及其他原因导致了十八世纪欧洲第二次鼠疫大流行的消失。
Yersinia pestis strains from Latvia show depletion of the pla virulence gene at the end of the second plague pandemic
古代基因组学研究已将鼠疫耶尔森氏菌（Y. pestis）鉴定为始于黑死病（1347-1353）的第二次鼠疫大流行（14-18世纪）的病原体。此次大流行中研究的鼠疫耶尔森氏菌菌株大多分离自西欧，人们对该细菌在东欧国家的多样性和微进化知之甚少。在本研究中，我们调查了从里加（拉脱维亚）两处墓地中发掘出的人类遗骸。历史证据表明，这些墓葬是17世纪鼠疫爆发的结果。我们从16具遗骸的牙齿中提取了DNA，并进行了散弹枪测序。宏基因组学数据分析显示，在四具遗骸中存在鼠疫耶尔森氏菌序列，证实这些被埋葬的个体是鼠疫的受害者。在两份样本中，鼠疫耶尔森氏菌DNA覆盖率足以进行基因组重建。随后的系统发育分析表明，里加菌株的多样性与已知的后黑死病基因组多样性相符。有趣的是，两株拉脱维亚分离株并未聚类在一起。此外，我们检测到含有pla基因的pPCP1质粒区域的覆盖度下降。进一步分析表明存在两个pPCP1质粒，一个含有pla基因区域，一个不含pla基因区域，并且只有一个细菌染色体，这表明同一种细菌携带两个不同的pPCP1质粒。此外，我们在大多数先前发表的后黑死病菌株中发现了相同的模式，但在黑死病菌株中没有发现。pla基因是人类感染和传播的重要毒力因子。因此，pla基因缺失的菌株的传播可能以及其他原因导致了十八世纪欧洲第二次鼠疫大流行的消失。
Ancient genomes in South Patagonia reveal population movements associated with technological shifts and geography
Nathan Nakatsuka · Nature Communications
Ancient genomes in South Patagonia reveal population movements associated with technological shifts and geography
Nathan Nakatsuka · Nature Communications
DOI: 10.1038/s41467-020-17656-w
